Is Corynebacterium pseudotuberculosis Gram-positive or negative?
Corynebacterium pseudotuberculosis, a Gram-positive bacterium is the causative agent of caseous lymphadenitis (CLA), a chronic disease of sheep, goats and other warm blooded animals.
Where does Corynebacterium pseudotuberculosis come from?
Corynebacterium pseudotuberculosis is a gram-positive, soil-dwelling bacterium. Infection occurs worldwide and is increasing in frequency in North America. In horses, external abscesses involving the ventral abdomen and pectoral region are the most common presentation (“pigeon fever”).
Is Corynebacterium pseudotuberculosis aerobic or anaerobic?
This bacterium is grown at 37°C under aerobic or anaerobic conditions, thus C. pseudotuberculosis is a facultative anaerobe.
What does Yersinia pseudotuberculosis cause?
Y. pseudotuberculosis causes self-limiting acute gastroenteritis and mesenteric lymphadenitis that mimics acute appendicitis. Enteritis is usually seen in children as opposed to the mesenteric adenitis seen in adults.  Symptoms include abdominal pain, fever, vomiting, and diarrhea.
What test would you do to confirm the identification of Yersinia pseudotuberculosis?
pseudotuberculosis may be identified by DNA colony hybridization or PCR (38). A convenient in vitro test for potential virulence in Y. enterocolitica and Y. pseudotuberculosis strains is the formation of small highly convex colonies with the uptake of congo red dye when grown at 35-37°C but not at 26°C (11).
What are the roles of Corynebacterium in causing disease?
Diphtheria is a serious infection caused by strains of bacteria called Corynebacterium diphtheriae that make a toxin (poison). It is the toxin that can cause people to get very sick. Diphtheria bacteria spread from person to person, usually through respiratory droplets, like from coughing or sneezing.
What are the symptoms of Yersiniosis?
Common symptoms in children are fever, abdominal pain, and diarrhea, which is often bloody. In older children and adults, right-sided abdominal pain and fever may be confused with symptoms of appendicitis. In a small proportion of cases, complications such as skin rash, joint pains, or a blood infection can occur.
What are the complications at pseudotuberculosis and enteric Yersiniosis?
Complications of Y pseudotuberculosis infection may include intussusception, bacteremia, septic arthritis, and disseminated infection, especially in immunocompromises or iron-overloaded patients.
Can C Corynebacterium pseudotuberculosis cause lymphangitis?
Corynebacterium pseudotuberculosis is the agent of Caseous lymphadenitis (CLA), but may also cause other chronic diseases such as ulcerative lymphangitis. C. pseudotuberculosis has as host small and large ruminants, causing significant economic losses, and there are already some cases in the literature of transmission in humans as well.
How does Corynebacterium pseudotuberculosis spread?
Corynebacterium pseudotuberculosis produces an exotoxin (phospholipase D) that damages endothelial and blood cell membranes. This process enhances the organisms’ ability to withstand phagocytosis. The infection spreads through the lymphatics to local lymph nodes.
What causes caseous lymphadenitis in sheep with pseudotuberculosis?
C. pseudotuberculosis is a significant pathogen in animals, particularly sheep, in which it causes caseous lymphadenitis.